Ohio State Cancer researchers validate a clinical test for fusion genes

(Ohio State University Wexner Medical Center) An assay that identifies a genetic change called gene fusions in solid tumors has been developed and validated. The assay is called OSU-SpARKFuse (Ohio State University-Spanning Actionable RNA Kinase Fusions). Targeted therapies are becoming increasingly available that block the activity of fusion genes. OSU-SpARKFuse was designed to accurately detect fusions when only one of the two genes is known, which allows for the discovery of novel gene fusion...